Primary Cutaneous Nodular Amyloidosis: A Rare Disease
نویسندگان
چکیده
© 2017 Indian Dermatology Online Journal | Published by Wolters Kluwer Medknow A 40‐year‐old male presented with a 6‐month history of a gradually progressing, painless, firm, 10 × 8 mm erythematous nodule on his nose [Figure 1]. Skin biopsy showed nodular deposition of eosinophilic, acellular, amyloid material in the entire dermis, which was surrounded by focal plasma cell infiltrate [Figure 2]. This material was congophilic [Figure 3] and demonstrated kappa light chain restriction on immunohistochemistry [Figure 4]. Systemic amyloidosis was ruled out by laboratory investigations, and thus, a diagnosis of primary nodular cutaneous amyloidosis, immunoglobulin light chain (AL) type was made.
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